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Seeing what Alzheimer saw

The ability to visualize brain pathology in living individuals with Alzheimer disease could change how the disease is diagnosed and drugs to treat it tested. A recently developed positron emission tomography tracer helps to image fibrillar amyloid-β and neurofibrillary tangles and brings us closer to this goal.

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Figure 1: Three generations of PET studies in Alzheimer disease.

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de Leon, M., Mosconi, L. & Logan, J. Seeing what Alzheimer saw. Nat Med 13, 129–131 (2007). https://doi.org/10.1038/nm0207-129

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