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ACE sets up fertilization

The ACE enzyme, a target of blood pressure medications, now gains a new function in mice. The enzyme cleaves proteins linked to the cell membrane by GPI linkages, an activity required for fertilization (pages 160–166).

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Figure 1: ACE in egg fertilization.

Ann Thomson

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Corvol, P. ACE sets up fertilization. Nat Med 11, 118–119 (2005). https://doi.org/10.1038/nm0205-118

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