Yet another mouse deafness gene encodes an unconventional myosin isozyme.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Avraham, K.B. et al. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nature Genet. 11, 369–375 (1995).
Markin, V.S. & Hudspeth, A.J. Gating-spring models of mechanoelectrical transduction by hair cells of the internal ear. Annu. Rev. Biophys. Biomol. Struct. 24, 59–83 (1995).
Lyon, M.F. & Searle, A.G. Genetic Variants and Strains of the Laboratory Mouse (Oxford University Press, Oxford, 1989).
Gibson, F. et al. A type VII myosin encoded by the mouse deafness gene shaker 1. Nature 374, 62–64 (1995).
Weil, D. et al. Defective myosin VIIA gene responsible for Usher syndrome type 1B. Nature 374, 60–61 (1995).
Deol, M.S. & Green, M.C. Snell's waltzer, a new mutation affecting behavior and the inner ear in the mouse. Genet. Res. 8, 339–345 (1966).
Sole, C.K., Derfler, B.H., Duyk, G.M. & Corey, D.P. Molecular cloning of myosins from bullfrog saccular macula: A candidate for the hair Cell adaptation motor. Auditory Neurosci. 1, 63–75 (1994).
Hasson, T. & Mooseker, M.S. Porcine myosin-VI: Characterization of a new mammalian unconventional myosin. J. Cell Biol. 127, 425–440 (1994).
Hasson, T. et al. Expression in cochlea and retina of myosin Vila, the gene product defective in Usher syndrome type 1B. Proc. Natl. Acad. Sci. USA 92, 9815–9819 (1995).
Tilney, L.G., Tllney, M.S. & DeRosier, D.J. Actin filaments, stereocilia, and hair cells: How cells count and measure. Annu. Rev. Cell Biol. 8, 257–274 (1992).
Gillespie, P.G., Wagner, M.C. & Hudspeth, A.J. Identification of a 120-kD hair-bundle myosin I located near stereociliary tips. Neuron 11, 581–594 (1993).
Metcalf, A.B., Chelliah, Y. & Hudspeth, A.J. Molecular cloning of a myosin Iβ isozyme that may mediate adaptation by hair cells of the bullfrog's internal ear. Proc. Natl. Acad. Sci. USA 91, 11821–11825 (1994).
Eatock, R.A., Corey, D.P. & Hudspeth, A.J. Adaptation of mechanoelectrical transduction in hair cells of the bullfrog’s sacculus. J. Neurosci. 7, 2821–2836 (1987).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gillespie, P. Deaf and dizzy mice with mutated myosin motors. Nat Med 2, 27–29 (1996). https://doi.org/10.1038/nm0196-27
Issue Date:
DOI: https://doi.org/10.1038/nm0196-27