Correspondence | Published:

Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development

Nature Medicine volume 17, pages 2526 (2011) | Download Citation

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    et al. Nat. Med. 16, 678–686 (2010).

  2. 2.

    et al. Nat. Med. 16, 687–693 (2010).

  3. 3.

    & Curr. Opin. Genet. Dev. 17, 71–77 (2007).

  4. 4.

    & Bone 47, 190–196 (2010).

  5. 5.

    et al. J. Cell Biol. 177, 451–464 (2007).

Download references


This paper was supported by US National Institutes of Health grant RO1 AR048191-06 to E.S.

Author information


  1. Endocrine Unit, Department of Medicine, Massachusetts General Hospital–Harvard Medical School, Boston, Massachusetts, USA.

    • Elisa Araldi
    • , Richa Khatri
    •  & Ernestina Schipani
  2. Division of Cancer and Radiation Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA.

    • Amato J Giaccia
  3. Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

    • M Celeste Simon


  1. Search for Elisa Araldi in:

  2. Search for Richa Khatri in:

  3. Search for Amato J Giaccia in:

  4. Search for M Celeste Simon in:

  5. Search for Ernestina Schipani in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Ernestina Schipani.

Supplementary information

PDF files

  1. 1.

    Supplementary Text and Figures

    Supplementary Fig. 1 and Supplementary Methods

About this article

Publication history



Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing