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Bone-breaking cancer treatment

A drug used to counteract low white blood cell counts in individuals with breast cancer may also be inducing bone metastases (pages 2627).

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Figure 1: Breast cancer cells produce factors such as PTHrP and GM-CSF, which enhance the formation of osteoclasts.

Katie Ris

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Roodman, G. Bone-breaking cancer treatment. Nat Med 13, 25–26 (2007). https://doi.org/10.1038/nm0107-25

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