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A human cellular model of amyotrophic lateral sclerosis

Stem cell–derived human motor neurons were used to investigate the cellular mechanisms underlying C9ORF72-related amyotrophic lateral sclerosis.

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Figure 1: Intronic repeats in C9ORF72 cause loss of human motor neurons.

Marina Corral Spence/Springer Nature

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Correspondence to Sergiu P Paşca.

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Marton, R., Paşca, S. A human cellular model of amyotrophic lateral sclerosis. Nat Med 24, 256–257 (2018). https://doi.org/10.1038/nm.4509

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