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A microbial protein that alleviates metabolic syndrome

Nature Medicine volume 23, pages 1112 (2017) | Download Citation

A recent study shows that pasteurization of Akkermansia muciniphila enhances the bacterium's ability to reduce fat mass and metabolic syndrome in mice with diet-induced obesity, and that Amuc_1100*, a thermostable outer-membrane protein of A. muciniphila, can reproduce these beneficial effects.

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References

  1. 1.

    & ISME J. 6, 1449–1458 (2012).

  2. 2.

    , , & Int. J. Syst. Evol. Microbiol. 54, 1469–1476 (2004).

  3. 3.

    , , , & Appl. Environ. Microbiol. 74, 1646–1648 (2008).

  4. 4.

    et al. Appl. Environ. Microbiol. 77, 6718–6721 (2011).

  5. 5.

    , & Microb. Pathog. (2016).

  6. 6.

    et al. Proc. Natl. Acad. Sci. USA 110, 9066–9071 (2013).

  7. 7.

    et al. Gut 63, 727–735 (2014).

  8. 8.

    , , , & Circulation 133, 2434–2446 (2016).

  9. 9.

    et al. Nat. Med. 23, 107–113 (2017).

  10. 10.

    et al. Front. Microbiol. 7, 1157 (2016).

Download references

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Affiliations

  1. Fernando Forato Anhê and André Marette are in the Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Québec, Canada, and the Institute of Nutrition and Functional Foods, Laval University, Québec, Canada.

    • Fernando Forato Anhê
    •  & André Marette

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to André Marette.

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DOI

https://doi.org/10.1038/nm.4261

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