A new study in humans links genetic variants associated with schizophrenia to changes in the expression of two genes, arsenite methyltransferase (AS3MT) and BLOC-1 related complex subunit 7 (BORCS7). Subsequent investigations provide compelling evidence that AS3MT is involved in the etiology of schizophrenia.
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Sleiman, P., Hakonarson, H. From schizophrenia risk locus to schizophrenia genes. Nat Med 22, 583–584 (2016). https://doi.org/10.1038/nm.4122
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DOI: https://doi.org/10.1038/nm.4122