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Cardiotoxicity in a dish: new insights for personalized therapy

A recent study identifies differences in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes from patients with breast cancer who were treated with doxorubicin and either did or did not develop cardiotoxicity. The results open up new avenues for the development of personalized therapy and the prevention of cardiotoxicity.

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Figure 1: Cardiac hiPSCs can give indications as to the cardiotoxicity of doxorubicin.

Kim Caesar/Nature Publishing Group

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Correspondence to Timothy J Kamp.

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T.J.K. is a consultant for Cellular Dynamics International.

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Biermann, M., Kamp, T. Cardiotoxicity in a dish: new insights for personalized therapy. Nat Med 22, 459–460 (2016). https://doi.org/10.1038/nm.4095

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