A new study demonstrates that dysregulation of proteostasis can be a transforming event in hematopoiesis that could prove to be therapeutically actionable for treatment of myeloproliferative neoplasms.
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LaFave, L., Levine, R. Targeting a regulator of protein homeostasis in myeloproliferative neoplasms. Nat Med 22, 20–21 (2016). https://doi.org/10.1038/nm.4028
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DOI: https://doi.org/10.1038/nm.4028