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Personalizing pancreatic cancer organoids with hPSCs

A new study using human pluripotent stem cell (hPSC)-derived human pancreatic organoids to model neoplastic transformation and cancer-derived human pancreatic tumor organoids for drug testing provides new personalized approaches to modeling and treating this malignancy.

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Figure 1: Modeling pancreatic cancer with personalized human organoids.

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Correspondence to Calvin J Kuo.

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C.J.K. is an inventor on a pending patent describing organoid culture methodologies.

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Zhang, H., Kuo, C. Personalizing pancreatic cancer organoids with hPSCs. Nat Med 21, 1249–1251 (2015). https://doi.org/10.1038/nm.3992

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