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A new Twist in kidney fibrosis

Kidney fibrosis is a main pathological component of chronic kidney disease. Two new studies pinpoint a partial epithelial-to-mesenchymal transition as a mechanism driving the development of kidney fibrosis, thus paving the way for novel treatments of fibrosis-associated diseases.

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Figure 1: Partial EMT promotes chronic kidney disease.

Marina Corral Spence/Nature Publishing Group


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Correspondence to Valery Krizhanovsky.

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Ovadya, Y., Krizhanovsky, V. A new Twist in kidney fibrosis. Nat Med 21, 975–977 (2015).

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