Autophagy and apoptosis are ancient processes that regulate cell fate under normal and disease conditions. A new study in mice identifies mammalian Ste20-like kinase-1 (Mst-1) as a missing link that interfaces between these pathways for cell survival and death during cardiac stress (pages 1478–1488).
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Katie Vicari
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Dhingra, R., Kirshenbaum, L. Mst-1 switches between cardiac cell life and death. Nat Med 19, 1367–1368 (2013). https://doi.org/10.1038/nm.3371
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DOI: https://doi.org/10.1038/nm.3371
