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Small airways, big challenge: measuring the unseen?

An imaging technique adapted to differentiate between chronic obstructive pulmonary disease phenotypes can identify small-airway pathophysiology, locate the disease and potentially track disease progression. This approach may be used as a biomarker to identify the small-airway lesion in chronic obstructive pulmonary disease, at an individual level in the clinic (pages 1711–1715).

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Figure 1: Pathological phenotypes of COPD and imaging biomarkers.

Debbie Maizels


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Correspondence to Salman Siddiqui.

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The authors declare no competing financial interests.

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Siddiqui, S., Usmani, O. Small airways, big challenge: measuring the unseen?. Nat Med 18, 1619–1621 (2012).

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