Noise-induced hearing loss is caused primarily by damage to auditory hair cells; however, humans are unable to regenerate damaged hair cells, necessitating the development of new therapeutic strategies to protect auditory hair cells. A new study suggests that the use of phosphodiesterase 5 (PDE5) inhibitors may provide a protective therapeutic route for hearing loss (pages 252–259).
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Change history
08 February 2012
In the version of this article initially published, vardenafil was incorrectly referred to as Cialis. The reference to Cialis has now been deleted in the text, and the title has been amended to 'An unheard benefit of phosphodiesterase inhibition'. The error has been corrected in the HTML and PDF versions of the article.
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Layman, W., Zuo, J. An unheard benefit of phosphodiesterase inhibition. Nat Med 18, 206–207 (2012). https://doi.org/10.1038/nm.2647
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DOI: https://doi.org/10.1038/nm.2647