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Signals for lymphocyte egress

Nature Immunology volume 6, pages 1215–1216 (2005)Cite this article

Lymphocyte egress from lymph nodes is thought to require signals on T cells for the initiation of exit movement. Another possibility is that signaling instead opens endothelial 'gates' through which lymphocytes pass.

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Figure 1: In untreated lymph nodes (blue cells, left), random lymphocyte migration proceeds at a velocity of 10–12 μm/min (arrows) in the cortex (top; reddish shading) and 6.5 μm/min in the medulla (light tan).

Katie Ris

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Authors and Affiliations

  1. Departments of Biomedical Engineering, Molecular Physiology and Biological Physics and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, 22908, Virginia, USA

    Klaus Ley

  2. Department of Biomedical Engineering and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, 22908, Virginia, USA

    Maggie Morris

Authors
  1. Klaus Ley
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  2. Maggie Morris
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Ley, K., Morris, M. Signals for lymphocyte egress. Nat Immunol 6, 1215–1216 (2005). https://doi.org/10.1038/ni1205-1215

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