The mitogen-activated protein kinases Erk and p38 transduce Toll-like receptor signals that lead to antigen capture by dendritic cells. New work identifies 'downstream' effector kinases essential for these responses and traces a pathway of mitogen-activated protein kinase signaling apparently unique to dendritic cells.
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Karin, M. Rsk Tolls the bell for endocytosis in DCs. Nat Immunol 8, 1197–1199 (2007). https://doi.org/10.1038/ni1107-1197
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DOI: https://doi.org/10.1038/ni1107-1197