Mature dendritic cells are considered terminally differentiated. However, this dogma is challenged by data showing culture-generated mature dendritic cells can further differentiate under the influence of stromal cells.
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References
Mellman, I. & Steinman, R.M. Cell 106, 255–258 (2001).
Shortman, K. & Liu, Y.-J. Nat. Rev. Immunol. 2, 153–163 (2002).
Zhang, M. et al. Nat. Immunol. 5, 1124–1133 (2004).
Inaba, K. et al. J. Exp. Med. 176, 1693–1702 (1992).
Sallusto, F. & Lanzavecchia, A. J. Exp. Med. 179, 1109–1118 (1994).
Caux, C., Vanbervliet, B., Massacrier, C., Durand, I. & Banchereau, J. Blood 87, 2376–2385 (1996).
Brasel, K., De Smedt, T., Smith, J.L. & Maliszewski, C.R. Blood 96, 3029–3039 (2000).
Winzler, C. et al. J. Exp. Med. 185, 317–328 (1997)
Kamath, A. et al. J. Immunol. 165, 6762–6770 (2000).
Kamath, A.T., Henri, S., Battye, F., Tough, D.F. & Shortman, K. Blood 100, 1734–1741 (2002)
Wilson, H.L., Ni, K. & O'Neill, H.C. Proc. Natl. Acad. Sci. USA 97, 4784–4789 (2000).
Laouar, Y. et al. Immunity 19, 903–912 (2003).
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Shortman, K., Wu, L. Are dendritic cells end cells?. Nat Immunol 5, 1105–1106 (2004). https://doi.org/10.1038/ni1104-1105
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DOI: https://doi.org/10.1038/ni1104-1105
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