Many models have been put forth to explain the function of CD4 T cell help in primary and memory CD8 T cell generation. New evidence suggests the licensing model may be the most physiologically relevant.
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Ashton-Rickardt, P. A license to remember. Nat Immunol 5, 1097–1098 (2004). https://doi.org/10.1038/ni1104-1097
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DOI: https://doi.org/10.1038/ni1104-1097
