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Cytokines, virokines and the evolution of immunity

Nature Immunology volume 1, pages 367368 (2000) | Download Citation

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In a new twist, the cytokine IL-10, if present when leukocytes are activated, can disconnect chemokine receptors from signaling for cell migration. The receptors act as a “sink” for soaking up chemokines, thus providing the perfect decoy.

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Author information

Affiliations

  1. University Division of Genomic Medicine, Royal Hallamshire Hospital, Sheffield S10 2JF, UK. s.dower@sher.ac.uk

    • Steven K. Dower

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DOI

https://doi.org/10.1038/80799

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