Translating mouse models into clinical therapies has never been easy. Immunotherapies for cancer also have to contend with an approval process designed for testing drugs. It may be necessary to consider different endpoints and objectives when evaluating the efficacy of these newer approaches.
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Srivastava, P. Immunotherapy of human cancer: lessons from mice. Nat Immunol 1, 363–366 (2000). https://doi.org/10.1038/808795
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DOI: https://doi.org/10.1038/808795