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Boosting p53 with interferon and viruses

Nature Immunology volume 4, pages 825–826 (2003)Cite this article

Interferon-α/β proteins are vital for innate immune responses to viruses. The tumor suppressor p53 mediates cell cycle arrest and apoptosis. A recent study in Nature reports that interferon-α/β stimulates p53 synthesis, demonstrating a hitherto unrecognized link.

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Figure 1: Stimulation of p53 gene transcription by IFN-α/β and p53 activation by virus infection.

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  1. New York University School of Medicine, New York, 10016, New York, USA

    Jan Vilček

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  1. Jan Vilček
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Vilček, J. Boosting p53 with interferon and viruses. Nat Immunol 4, 825–826 (2003). https://doi.org/10.1038/ni0903-825

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