Type I interferons are produced by almost all nucleated cells in response to virus infection. MafB is now shown to modulate the efficiency of interferon production by setting a threshold for IRF3-dependent transcription.
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Katie Vicari
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Motohashi, H., Igarashi, K. MafB as a type I interferon rheostat. Nat Immunol 11, 695–696 (2010). https://doi.org/10.1038/ni0810-695
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DOI: https://doi.org/10.1038/ni0810-695
