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Dead man walking: how thymocytes scan the medulla

The thymic medulla provides a unique milieu for the induction of T cell tolerance. New work now provides a first glimpse of how thymocytes scan this microenvironment and thus maximize their chances of encountering self antigen.

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Figure 1: Linking the topology and timing of T cell development with thymocyte motility.


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Klein, L. Dead man walking: how thymocytes scan the medulla. Nat Immunol 10, 809–811 (2009).

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