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Arresting autoimmunity by blocking β-arrestin 1

Nature Immunology volume 8, pages 791–792 (2007)Cite this article

The regulation of T cell survival and apoptosis contributes to the pathogenesis of autoimmune disease. A new study shows that the transcriptional regulator β-arrestin 1 enhances antiapoptotic Bcl-2 in T cells, which can heighten autoimmune disease.

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Figure 1: Regulation of transcription of Bcl2 by β-arrestin 1.

Katie Ris

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Authors and Affiliations

  1. Terra J. Frederick and Stephen D. Miller are in the Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. s-d-miller@northwestern.edu,

    Terra J Frederick & Stephen D Miller

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  1. Terra J Frederick
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  2. Stephen D Miller
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Frederick, T., Miller, S. Arresting autoimmunity by blocking β-arrestin 1. Nat Immunol 8, 791–792 (2007). https://doi.org/10.1038/ni0807-791

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