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NIAID workshop on immunity to malaria: addressing immunological challenges

The US National Institute of Allergy and Infectious Diseases convened a workshop of malaria investigators and immunologists to foster collaborations and attract more immunologists into malaria research. Discussions highlighted research gaps and underscored the incomplete understanding of basic immune mechanisms that contribute to the pathogenesis of or protection against malaria.

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Figure 1: Estimated incidence of malaria in 2006.
Figure 2: Women wait with their sick babies receiving treatment for malaria.
Figure 3: Population indices of immunity in an endemic area of P. falciparum transmission.
Figure 4: Life cycle of the malaria parasite (Plasmodium species).

References

  1. World Health Organization. WHO World Malaria Report 2008 <http://www.who.int/malaria/wmr2008/malaria2008.pdf> (2008).

  2. Pierce, S.K. & Miller, L.H. J. Immunol. 182, 5171–5177 (2009).

    Article  CAS  Google Scholar 

  3. Coban, C. et al. Trends Microbiol. 15, 271–277 (2007).

    Article  CAS  Google Scholar 

  4. Langhorne, J. et al. Nat. Immunol. 9, 725–732 (2008).

    Article  CAS  Google Scholar 

  5. National Institute of Allergy and Infectious Diseases. Life Cycle of the Malaria Parasite. <http://www3.niaid.nih.gov/topics/Malaria/lifecycle.htm> (14 April 2009)

  6. Coban, C. et al. J. Exp. Med. 201, 19–25 (2005).

    Article  CAS  Google Scholar 

  7. McCall, M.B. et al. J. Immunol. 179, 162–171 (2007).

    Article  CAS  Google Scholar 

  8. Wherry, E.J. et al. Immunity 27, 670–684 (2007).

    Article  CAS  Google Scholar 

  9. Belkaid, Y. et al. Immunol. Rev. 212, 287–300 (2006).

    Article  CAS  Google Scholar 

  10. Cohen, S. et al. Nature 192, 733–737 (1961).

    Article  CAS  Google Scholar 

  11. McGregor, I.A. & Carrington, S.P. Trans. R. Soc. Trop. Med. Hyg. 57, 170–175 (1963).

    Article  Google Scholar 

  12. Pierce, S.K. Immunol. Res. 43, 85–97 (2008).

    Article  Google Scholar 

  13. Moir, S. et al. J. Exp. Med. 205, 1797–1805 (2008).

    Article  CAS  Google Scholar 

  14. Vaughan, K. et al. Parasite Immunol. 31, 78–97 (2009).

    Article  CAS  Google Scholar 

  15. Muehlenbachs, A. et al. Proc. Natl. Acad. Sci. USA 105, 14488–14491 (2008).

    Article  CAS  Google Scholar 

  16. Papathanasiou, P. & Goodnow, C.C. Annu. Rev. Genet. 39, 241–262 (2005).

    Article  CAS  Google Scholar 

  17. Beutler, B. et al. Annu. Rev. Immunol. 24, 353–389 (2006).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We thank the following workshop participants for discussions and contributions: B. Beutler, C.A. Biron, P. Crompton, O. Doumbo, P. Duffy, K. Fitzgerald, D. Golenbock, H. Gans, R. Gazzinelli, M. Good, J.T. Harty, P. Holt, S. Kappe, J.W. Kazura, J. Langhorne, T.M. Laufer, R.F.G. Leke, C. Long, E.O. Long, J. McCarthy, M. McHeyzer-Williams, L.H. Miller, S.D. Miller, G. Mor, C. Norbury, S.K. Pierce, E. Riley, L. Schofield, P. Scott, R. Seder, A. Sette, A. Sher, E.M. Shevach, J.D. Smith, G. Snounou, T.A. Springer, M.M. Stevenson, D.W. Taylor, M.Walgren, C.-R. Wang, T.E. Wellems, R. Wetsel, E.J. Wherry and F.P. Zavala. We also thank G. Folkers, H. Quill and N. Touchette for discussions and editorial comments.

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Augustine, A., Hall, B., Leitner, W. et al. NIAID workshop on immunity to malaria: addressing immunological challenges. Nat Immunol 10, 673–678 (2009). https://doi.org/10.1038/ni0709-673

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