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Erg in stem cells: a function emerges

Transcription factors of the Ets family are important for mammalian development. A genetic screen now finds that the Ets family member Erg is essential for definitive hematopoiesis and adult hematopoietic stem cell function.

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Figure 1: A point mutation in Erg with considerable hematopoietic effects.

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Rothenberg, E. Erg in stem cells: a function emerges. Nat Immunol 9, 714–716 (2008). https://doi.org/10.1038/ni0708-714

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