A hierarchy of stem cells has been identified within leukemias, providing a more complex view of how these self-renewing populations parallel the normal stem cell compartment. As the resemblance between normal and malignant stem cells deepens, new opportunities for understanding and treating malignancy emerge.
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Scadden, D. Cancer stem cells refined. Nat Immunol 5, 701–703 (2004). https://doi.org/10.1038/ni0704-701
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DOI: https://doi.org/10.1038/ni0704-701
