A family of intracellular molecules called NODs has been proposed to sense bacteria within the cell. New data now show that NOD1 senses a distinct bacterial component and may thus be important in responding to bacteria with this molecular signature.
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References
Inohara, N., Ogura, Y., Chen, F.F., Muto, A. & Nunez, G. J. Biol. Chem. 276, 2551–2554 (2001).
Chamaillard, M. et al. Nat. Immunol. 702–707 (2003).
Girardin, S.E. et al. Science 300, 1584–1587 (2003).
Girardin, S.E. et al. J. Biol. Chem. 278, 8869–8872 (2003).
Inohara, N. et al. J. Biol. Chem. 278, 5509–5512 (2003).
Inohara, N. & Nunez, G. Nat. Rev. Immunol. 3, 371–382 (2003).
Inohara, N. et al. J. Biol. Chem. 274, 14560–14567 (1999).
Staskawicz, B.J., Mudgett, M.B., Dangl, J.L. & Galan, J.E. Science 292, 2285–2289 (2001).
Holt, B.F., Hubert, D.A. & Dangl, J.L. Curr. Opin. Immunol. 15, 20–25 (2003).
Leulier, F. et al. Nat. Immunol. 4, 478–484 (2003).
Kobayashi, K. et al. Nature 416, 194–199 (2002).
Chin, A.I. et al. Nature 416, 190–194 (2002).
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Kobayashi, K., Eynon, E. & Flavell, R. Intracellular debugging. Nat Immunol 4, 652–654 (2003). https://doi.org/10.1038/ni0703-652
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DOI: https://doi.org/10.1038/ni0703-652