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RNA interference: antiviral defense and genetic tool

Nature Immunology volume 3, pages 597–599 (2002)Cite this article

Higher eukaryotes can mount antiviral immune responses induced by dsRNA. This process, called RNA interference, is sequence specific and can therefore be used to target gene expression.

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Figure 1: Biosynthesis of small, noncoding RNAs.

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  1. Howard Hughes Medical Institute and Department of Molecular Genetics and Microbiology, Duke University Medical Center, Box 3025, Durham, 27710, NC, USA

    Bryan R. Cullen

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  1. Bryan R. Cullen
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Cullen, B. RNA interference: antiviral defense and genetic tool. Nat Immunol 3, 597–599 (2002). https://doi.org/10.1038/ni0702-597

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