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Leukocyte chemotaxis: from lysosomes to motility

Nature Immunology volume 11, pages 463–464 (2010)Cite this article

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Chemoattractants direct the extravasation of leukocytes to the site of immune response. New data highlight the role of synaptotagmins and Rab proteins in leukocyte chemotaxis.

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Figure 1: Leukocytes follow a chemotactic stimulus by sensing the gradient and generating a continuous cycling of adhesive events, cytoskeleton polymerization and plasma membrane remodeling.

Kim Caesar

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Authors and Affiliations

  1. Gabriela Constantin and Carlo Laudanna are in the Department of Pathology, Division of General Pathology, University of Verona, Verona, Italy,

    Gabriela Constantin & Carlo Laudanna

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  1. Gabriela Constantin
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  2. Carlo Laudanna
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Correspondence to Carlo Laudanna.

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The authors declare no competing financial interests.

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Constantin, G., Laudanna, C. Leukocyte chemotaxis: from lysosomes to motility. Nat Immunol 11, 463–464 (2010). https://doi.org/10.1038/ni0610-463

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