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DNA deaminases converge on adaptive immunity

Nature Immunology volume 8, pages 551553 (2007) | Download Citation

AID acts to further refine the immunoglobulin response in fish, birds and mammals. Now, evidence is uncovered to suggest AID actually arose early in evolution and can diversify antigen receptors in lampreys.

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Author information

Affiliations

  1. David G. Schatz is with the Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. david.schatz@yale.edu

    • David G Schatz

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Competing interests

The author declares no competing financial interests.

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DOI

https://doi.org/10.1038/ni0607-551

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