T helper cells that produce interleukin 17 can promote a range of immune-mediated inflammatory diseases. Papers in Nature and Immunity suggest transforming growth factor-β promotes the differentiation of these pathogenic cells.
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Cua, D., Kastelein, R. TGF-β, a 'double agent' in the immune pathology war. Nat Immunol 7, 557–559 (2006). https://doi.org/10.1038/ni0606-557
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DOI: https://doi.org/10.1038/ni0606-557
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