Plasmacytoid dendritic cells selectively express Toll-like receptors 7 and 9 and respond to virus infection by triggering massive interferon production, a pathway regulated by osteopontin expressed in plasmacytoid dendritic cells.
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Cao, W., Liu, YJ. Opn: key regulator of pDC interferon production. Nat Immunol 7, 441–443 (2006). https://doi.org/10.1038/ni0506-441
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DOI: https://doi.org/10.1038/ni0506-441
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