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Toll signaling: RIPping off the TNF pathway

Nature Immunology volume 5, pages 472–474 (2004)Cite this article

Toll-like receptors (TLRs) use multiple downstream signaling pathways. New data suggest that components of the tumor necrosis factor receptor signaling pathway are involved in signal transduction by certain TLR family members.

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Figure 1: Signaling pathways downstream of the TLR adaptor Trif.

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Authors and Affiliations

  1. Section of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, 06520, Connecticut, USA

    Gregory M Barton & Ruslan Medzhitov

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  1. Gregory M Barton
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  2. Ruslan Medzhitov
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Barton, G., Medzhitov, R. Toll signaling: RIPping off the TNF pathway. Nat Immunol 5, 472–474 (2004). https://doi.org/10.1038/ni0504-472

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