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RNA AIDs DNA

Experiments based on the requirement for immunoglobulin gene transcription provide new insights into the elusive role played by AID in immunoglobulin class switching and hypermutation.

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Figure 1: The R-loop model of class switch recombination.

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Correspondence to David G. Schatz.

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Fugmann, S., Schatz, D. RNA AIDs DNA. Nat Immunol 4, 429–430 (2003). https://doi.org/10.1038/ni0503-429

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