The development and function of TCRαβ+CD8αα+ intraepithelial lymphocytes remain poorly understood. These cells are now shown to require transforming growth factor-β for development and proper expression of characteristic surface homodimers of CD8α.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Konkel, J.E. et al. Nat. Immunol. 12, 312–319 (2011).
Rocha, B., Vassalli, P. & Guy-Grand, D. J. Exp. Med. 173, 483–486 (1991).
Guy-Grand, D. et al. J. Exp. Med. 173, 471–481 (1991).
Guy-Grand, D. et al. J. Exp. Med. 197, 333–341 (2003).
Eberl, G. & Littman, D.R. Science 305, 248–251 (2004).
Gangadharan, D. et al. Immunity 25, 631–641 (2006).
Baldwin, T.A., Hogquist, K.A. & Jameson, S.C. J. Immunol. 173, 6515–6520 (2004).
Cruz, D. et al. J. Exp. Med. 188, 255–265 (1998).
Regnault, A., Cumano, A., Vassalli, P., Guy-Grand, D. & Kourilsky, P. J. Exp. Med. 180, 1345–1358 (1994).
Ming, O.L., Sanjabi, S. & Flavell, R.A. Immunity 25, 455–471 (2006).
Liu, Y. et al. Nat. Immunol. 9, 632–640 (2008).
Ouyang, W., Beckett, O., Ma, Q. & Li, M.O. Immunity 32, 642–653 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Kappes, D. Developing intestinal fortitude. Nat Immunol 12, 281–282 (2011). https://doi.org/10.1038/ni0411-281
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni0411-281
