HIV-1 is unable to infect cells from most nonhuman primates. In a recent Nature paper, a cellular protein of monkey cells, TRIM5α, was shown to be responsible for this inhibition.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
PcTrim prevents early infection with white spot syndrome virus by inhibiting AP1-induced endocytosis
Cell Communication and Signaling Open Access 08 May 2023
-
Revisiting HIV-1 uncoating
Retrovirology Open Access 17 November 2010
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Sheehy, A.M., Gaddis, N.C., Choi, J.D. & Malim, M.H. Nature 418, 646–650 (2002).
Stremlau, M. et al. Nature 427, 848–853 (2004).
Pornillos, O., Garrus, J.E. & Sundquist, W.I. Trends Cell Biol. 12, 569–579 (2002).
Sheehy, A.M., Gaddis, N.C. & Malim, M.H. Nat. Med. 9, 1404–1407 (2003).
Marin, M., Rose, K.M., Kozak, S.L. & Kabat, D. Nat. Med. 9, 1398–1403 (2003).
Bieniasz, P.D. Trends Microbiol. 11, 286–291 (2003).
Owens, C.M., Yang, P.C., Gottlinger, H. & Sodroski, J. J. Virol. 77, 726–731 (2003).
Turelli, P. et al. Mol. Cell. 7, 1245–1254 (2001).
Berthoux, L. et al. J. Virol. 77, 3167–3180 (2003).
Towers, G.J. et al. Nat. Med. 9, 1138–1143 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Stevenson, M. TRIMming HIV-1's mainsail. Nat Immunol 5, 355–356 (2004). https://doi.org/10.1038/ni0404-355
Issue Date:
DOI: https://doi.org/10.1038/ni0404-355
This article is cited by
-
PcTrim prevents early infection with white spot syndrome virus by inhibiting AP1-induced endocytosis
Cell Communication and Signaling (2023)
-
Revisiting HIV-1 uncoating
Retrovirology (2010)