Epithelial cells responding to inflammatory stimuli can initiate class switching and antibody secretion in naive B cells. TSLP, BAFF and SLPI are epithelial cell–derived local regulators of effector B cell responses in mucosal environments.
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McHeyzer-Williams, M. Local sentries for class switching. Nat Immunol 8, 230–232 (2007). https://doi.org/10.1038/ni0307-230
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DOI: https://doi.org/10.1038/ni0307-230