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Defining 'stemness': Notch and Wnt join forces?

Nature Immunology volume 6, pages 234–236 (2005)Cite this article

Self-renewal of hematopoietic stem cells allows life-long production of blood cells. Notch signaling is critically involved in this process by maintaining a pool of self-renewing hematopoietic stem cells.

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Figure 1: Notch loss-of-function approaches and effects on HSCs.

K.R.

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  1. Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, 221 84, Sweden

    Sten Eirik W Jacobsen

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  1. Sten Eirik W Jacobsen
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Jacobsen, S. Defining 'stemness': Notch and Wnt join forces?. Nat Immunol 6, 234–236 (2005). https://doi.org/10.1038/ni0305-234

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