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The right team at the right time to go for a home run: tyrosine kinase activation by the TCR

Nature Immunology volume 11, pages 101–104 (2010)Cite this article

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Abstract

The TCR signals via cytoplasmic tyrosine kinases. Art Weiss recounts discoveries that led to early understanding of these events.

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Acknowledgements

I thank M. Matloubian, J. Imboden and T. DeFranco for reading this essay and for suggestions; the students, postdoctoral fellows and technicians whom I have worked with over the years (and regret being unable to discuss all their work); M. Mollenauer and T. Kadlecek, who have worked with me for more than two decades and have ensured that the laboratory has been a welcoming, productive and fun place to do research; J. Stobo and F. Fitch for guidance and advice during my training; my colleagues at UCSF who have made this public institution a very special place; and the National Institutes of Health, Rosalind Russell Medical Research Center for Arthritis and the Howard Hughes Medical Institute for support that made this work possible.

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  1. Departments of Medicine and of Microbiology and Immunology, Arthur Weiss is with the Howard Hughes Medical Institute, Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, San Francisco, California, USA.,

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Correspondence to Arthur Weiss.

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Weiss, A. The right team at the right time to go for a home run: tyrosine kinase activation by the TCR. Nat Immunol 11, 101–104 (2010). https://doi.org/10.1038/ni0210-101

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