The immune system has co-evolved with microbes that cause acute infectious disease. Immune responses must be appropriate to allow survival of both the individual and the species. These responses involve complex interactions that often go unmeasured.
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Zinkernagel, R. On observing and analyzing disease versus signals. Nat Immunol 8, 8–10 (2007). https://doi.org/10.1038/ni0107-8
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DOI: https://doi.org/10.1038/ni0107-8
