Multiple regulatory cascades control inflammatory gene expression. The responsive loci need to be prepared to bind the inducing regulatory factors, and such changes can be invoked by p38-dependent histone modification.
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Muegge, K. Preparing the target for the bullet. Nat Immunol 3, 16–17 (2002). https://doi.org/10.1038/ni0102-16
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DOI: https://doi.org/10.1038/ni0102-16
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