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Lost GRP on cytotoxicity?

Nature Immunology volume 17, pages 1339–1340 (2016)Cite this article

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Deficiency in the RASGRP1 guanine-nucleotide-exchange factor leads to a novel primary immunodeficiency with impaired activation and proliferation of T cells and B cells and defective killing by cytotoxic T cells and natural killer cells.

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Figure 1: RasGRP1's domains, regulation, signaling and function in immune cells.

Change history

  • 12 December 2016

    In the version of this article initially published, the surname of the first author for the linked article was stated incorrectly (Saltzer). The correct name is Salzer. The error has been corrected in the HTML and PDF versions of the article.

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Authors and Affiliations

  1. Jeroen P. Roose is in the Department of Anatomy, University of California San Francisco, San Francisco, California, USA.,

    Jeroen P Roose

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  1. Jeroen P Roose
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Correspondence to Jeroen P Roose.

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Roose, J. Lost GRP on cytotoxicity?. Nat Immunol 17, 1339–1340 (2016). https://doi.org/10.1038/ni.3620

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