Targeting of innate lymphoid cells, the innate counterparts of T cells, might allow early direction of the immune system into the appropriate response during preventive and therapeutic strategies aimed at pathogens and inflammatory pathologies.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2
Immunity & Ageing Open Access 28 November 2018
-
NK cells of the oldest seniors represent constant and resistant to stimulation high expression of cellular protective proteins SIRT1 and HSP70
Immunity & Ageing Open Access 06 March 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Eberl, G., Colonna, M., Di Santo, J.P. & McKenzie, A.N. Science 348, aaa6566 (2015).
Brennan, P.J., Brigl, M. & Brenner, M.B. Nat. Rev. Immunol. 13, 101–117 (2013).
Hepworth, M.R. et al. Nature 498, 113–117 (2013).
Oliphant, C.J. et al. Immunity 41, 283–295 (2014).
Satoh-Takayama, N. et al. Immunity 29, 958–970 (2008).
Zheng, Y. et al. Nat. Med. 14, 282–289 (2008).
Hernández, P.P. et al. Nat. Immunol. 16, 698–707 (2015).
Van Maele, L. et al. J. Infect. Dis. 210, 493–503 (2014).
Klose, C.S. et al. Nature 494, 261–265 (2013).
Klose, C.S. et al. Cell 157, 340–356 (2014).
Abt, M.C. et al. Cell Host Microbe 18, 27–37 (2015).
Moro, K. et al. Nature 463, 540–544 (2010).
Neill, D.R. et al. Nature 464, 1367–1370 (2010).
Monticelli, L.A. et al. Nat. Immunol. 12, 1045–1054 (2011).
Sonnenberg, G.F. et al. Science 336, 1321–1325 (2012).
Buonocore, S. et al. Nature 464, 1371–1375 (2010).
Geremia, A. et al. J. Exp. Med. 208, 1127–1133 (2011).
Bernink, J.H. et al. Nat. Immunol. 14, 221–229 (2013).
Fuchs, A. et al. Immunity 38, 769–781 (2013).
Lee, M. et al. Cell 160, 74–87 (2014).
Qiu, Y. et al. Cell 157, 1292–1308 (2014).
Burcelin, R., Garidou, L. & Pomié, C . Semin. Immunol. 24, 67–74 (2012).
Wensveen, F.M. et al. Nat. Immunol. 16, 376–385 (2015).
Kim, H.Y. et al. Nat. Med. 20, 54–61 (2014).
Halim, T.Y. et al. Immunity 40, 425–435 (2014).
Salimi, M. et al. J. Exp. Med. 210, 2939–2950 (2013).
Kim, B.S. et al. Sci. Transl. Med. 5, 170ra116 (2013).
Li, D. et al. J. Allergy Clin. Immunol. 134, 1422–1432 (2014).
McHedlidze, T. et al. Immunity 39, 357–371 (2013).
Kruglov, A.A. et al. Science 342, 1243–1246 (2013).
Magri, G. et al. Nat. Immunol. 15, 354–364 (2014).
Lochner, M. et al. J. Exp. Med. 208, 125–134 (2011).
Aparicio-Domingo, P. et al. J. Exp. Med. 212, 1783–1791 (2015).
Hanash, A.M. et al. Immunity 37, 339–350 (2012).
Acknowledgements
Supported by the Agence Nationale de la Recherche (S.C. and J.M.) and the European Molecular Biology Organization (T.A.).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Cording, S., Medvedovic, J., Aychek, T. et al. Innate lymphoid cells in defense, immunopathology and immunotherapy. Nat Immunol 17, 755–757 (2016). https://doi.org/10.1038/ni.3448
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni.3448
This article is cited by
-
Evaluation of circulating innate lymphoid cells in the early pathogenesis of mouse colorectal carcinoma
Comparative Clinical Pathology (2023)
-
CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2
Immunity & Ageing (2018)
-
NK cells of the oldest seniors represent constant and resistant to stimulation high expression of cellular protective proteins SIRT1 and HSP70
Immunity & Ageing (2018)
-
Jak3 deficiency blocks innate lymphoid cell development
Mucosal Immunology (2018)
-
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
Nature (2017)