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Putting the brakes on ILC2 cells

Nature Immunology volume 17, pages 4344 (2016) | Download Citation

Immune responses are characterized by the concerted actions of both effector mechanisms and regulatory mechanisms. Signaling via the transcription factor STAT1 downstream of receptors for interferons and interleukin 27 (IL-27) can suppress type 2 immune responses induced by group 2 innate lymphoid cells (ILCs).

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Author information

Affiliations

  1. Christina Stehle and Chiara Romagnani are in the Department of Innate Immunity, Deutsches Rheuma Forschungszentrum Berlin, Leibniz-Gemeinschaft, Berlin, Germany.

    • Christina Stehle
    •  & Chiara Romagnani
  2. Philippe Saikali is in the Department of Experimental Immunology, Deutsches Rheuma Forschungszentrum Berlin, Leibniz-Gemeinschaft, Berlin, Germany.

    • Philippe Saikali

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Chiara Romagnani.

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DOI

https://doi.org/10.1038/ni.3353

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