Optimal immunosuppression by regulatory T cells (Treg cells) relies on gene-expression and signaling modules that are customized to the target cell. The kinase CK2 is upregulated in Treg cells and controls a newly identified Treg cell subset that acts on dendritic cells to suppress T helper type 2 inflammatory responses in the lungs.
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Sawant, D., Dent, A. It takes CK2 to suppress TH2. Nat Immunol 16, 224–225 (2015). https://doi.org/10.1038/ni.3104
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DOI: https://doi.org/10.1038/ni.3104
