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Neutrophil recruitment: perivascular macrophages 'duke it out' with Staphylococcus aureus

Control of infection with Staphylococcus aureus relies on the production of neutrophil-recruiting chemokines by perivascular macrophages. S. aureus counterattacks by secreting α-hemolysin, which lyses tissue macrophages.

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Figure 1: PVMs are lysed by Hla.

Marina Corral Spence

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Correspondence to Francis W Luscinskas.

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Luscinskas, F. Neutrophil recruitment: perivascular macrophages 'duke it out' with Staphylococcus aureus. Nat Immunol 15, 10–11 (2014). https://doi.org/10.1038/ni.2793

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