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The danger of sex and death in Scarf1−/− autoimmune mice

Nature Immunology volume 14, pages 888–889 (2013)Cite this article

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In the absence of the SCARF1 scavenger system in mice, the load of 'dangerous' molecules can increase, inducing features of lupus in a sex-dependent process. These findings highlight the interplay of death and sex in the generation of autoimmunity.

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Figure 1: The role of SCARF1 in the pathogenesis of autoimmunity.

Marina Corral Spence

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  1. David S. Pisetsky is with the Durham VA Medical Center, Medical Research Service, Durham, North Carolina, USA, and Duke University Medical Center, Durham, North Carolina, USA.,

    David S Pisetsky

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  1. David S Pisetsky
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Correspondence to David S Pisetsky.

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Pisetsky, D. The danger of sex and death in Scarf1−/− autoimmune mice. Nat Immunol 14, 888–889 (2013). https://doi.org/10.1038/ni.2684

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