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IL-17-producing B cells combat parasites

Nature Immunology volume 14, pages 419421 (2013) | Download Citation

Interleukin 17 (IL-17) confers protection against Trypanosoma cruzi. Surprisingly, B cells are the relevant source, producing IL-17 via a unique pathway independent of the transcription factor RORγt, induced by T. cruzi trans-sialidase.

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Author information

Affiliations

  1. Beatriz León and Frances E. Lund are in the Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

    • Beatriz León
    •  & Frances E Lund

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Frances E Lund.

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DOI

https://doi.org/10.1038/ni.2593

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